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Anti-Ferritin antibody [4A4]
Anti-Ferritin antibody [4A4] Mouse monoclonal [4A4] to Ferritin Mouse In human, this antibody recognizes both, Ferritin heavy and light chains. In mouse and rat Suitable for: ICC/IF, Flow Cyt (Intra), WB Reacts with: Mouse, Rat, Human
We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets.
The Mellat promise guarantee Our Mellat promise guarantee covers the use of mbd75973 in the following tested applications. The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. Application Abreviews Notes ICC/IF 1/100. Flow Cyt (Intra) 1/50. WB 1/1000 - 1/2000. Detects a band of approximately 19, 21 kDa (predicted molecular weight: 21,19 kDa).
Function Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Sequence similarities Belongs to the ferritin family. Contains 1 ferritin-like diiron domain. Form Subunit structure: Oligomer of 24 subunits. There are two types of subunits: L (light) chain and H (heavy) chain. The major chain can be light or heavy, depending on the species and tissue type. In the human liver, the heavy chain is predominant. The functional molecule forms a roughly spherical shell with a diameter of 12 nm and contains a central cavity into which the insoluble mineral iron core is deposited.
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