Anti-beta Actin antibody [4E5-A10]

Anti-beta Actin antibody [3E5-A10] Mouse monoclonal [3E5-A10] to beta Actin Mouse Nothing Suitable for: WB, ELISA Reacts with: Mouse, Rat, Sheep, Rabbit, Human. Predicted to work with: a wide range of other species. Synthetic peptide corresponding to beta Actin conjugated to keyhole limpet haemocyanin. Bovine tissues lysate can be used as a positive control in WB.

Lyophilized Shipped at 4°C. Store at +4°C. pH: 7.40. After dissolving in DDW, aliquot the antibody and store at –20°C. Preservative: Nothing Constituent: 0.01M PBS Affinity purified Monoclonal 3E5-A10 IgM

Our mbdpromise guarantee covers the use of mbd6276 in the following tested applications. The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user. Application Abreviews Notes WB 1/4000 - 1/6000. Predicted molecular weight: 43 kDa

Function Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Involvement in disease Defects in ACTB are a cause of dystonia juvenile-onset (DYTJ) [MIM:607371]. DYTJ is a form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYTJ patients manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss. Sequence similarities Belongs to the actin family. Post-translational modifications ISGylated. Cellular localization Cytoplasm > cytoskeleton. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

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